The average bus between Penn Station and Upper East Side takes 4h 45m and the fastest bus takes 4h 5m. The bus service runs several times per day from Penn Station to Upper East Side. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Penn Station and Upper East Side. The earliest departure is at 12:39 AM at night, and the last departure from Penn Station is at 9:59 PM which arrives into Upper East Side at 3:38 AM. All services require a transfer at MCCULLOH ST & PRESTON ST nb and take an average of 4h 45m. The schedules shown below are for the next available departures.


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4h 59m • 2 changesWant to know about travelling from Penn Station to Upper East Side? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Penn Station to Upper East Side. However, there are services departing from Baltimore Downtown Bus Station and arriving at New York Midtown station via New York Midtown station. The journey, including transfers, takes approximately 4h 45m.
Penn Station to Upper East Side bus services, operated by Flixbus USA, depart from Baltimore Downtown Bus Station.
Penn Station to Upper East Side bus services, operated by Flixbus USA, arrive at New York Midtown station.
The distance between Penn Station and Upper East Side is 279.6 km. The road distance is 309 km.
Flixbus USA operates a bus from Baltimore Downtown Bus Station to New York Midtown hourly. Tickets cost $35–60 and the journey takes 3h 30m.