The average bus between Penzance and Brighton takes 11h 21m and the fastest bus takes 10h 25m. The bus service runs several times per day from Penzance to Brighton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Penzance and Brighton. The earliest departure is at 4:45 AM at night, and the last departure from Penzance is at 9:25 PM which arrives into Brighton at 7:50 AM. All services require a transfer, and take on average 11h 21m. The schedules shown below are for the next available departures.

12h 27m • 1 change

11h 2m • 1 change
Arrives next day

10h 25m • 1 change

12h 27m • 1 change

11h 2m • 1 change
Arrives next day

10h 25m • 1 change

12h 2m • 1 change

11h 37m • 1 change
Arrives next day

10h 25m • 1 change

12h 2m • 1 change

11h 37m • 1 change
Arrives next day

10h 25m • 1 change
Want to know about travelling from Penzance to Brighton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Penzance to Brighton. However, there are services departing from Penzance station and arriving at Brighton station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 11h 21m.
Penzance to Brighton bus services, operated by National Express, depart from Bus Station.
Penzance to Brighton bus services, operated by National Express, arrive at Preston Circus station.
Book your Penzance to Brighton bus tickets online with National Express.
The distance between Penzance and Brighton is 390 km. The road distance is 576 km.
You can take a bus from Bus Station to Preston Circus via Heathrow Central Bus Station in around 10h 27m.