The average bus between Perugia and Frankfurt am Main takes 19h 51m and the fastest bus takes 18h 50m. The bus service runs several times per day from Perugia to Frankfurt am Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Perugia and Frankfurt am Main. The earliest departure is at 11:25 AM in the morning, and the last departure from Perugia is at 5:15 PM which arrives into Frankfurt am Main at 1:30 PM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 19h 51m. The schedules shown below are for the next available departures.
Arrives next day

18h 50m • 1 change
Arrives next day

20h 55m • 1 change
Arrives next day

18h 50m • 1 change
Arrives next day

20h 15m • 1 change
Want to know about travelling from Perugia to Frankfurt am Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Perugia to Frankfurt am Main. However, there are services departing from Perugia station and arriving at Frankfurt am Main station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 19h 51m.
Perugia to Frankfurt am Main bus services, operated by FlixBus, depart from Perugia station.
Perugia to Frankfurt am Main bus services, operated by FlixBus, arrive at Mühlheim am Main station.
Book your Perugia to Frankfurt am Main bus tickets online with FlixBus.
The distance between Perugia and Frankfurt am Main is 828.3 km. The road distance is 1,237 km.
You can take a bus from Perugia to Frankfurt Konstablerwache via Florence Villa Constanza Bus Station, Mühlheim am Main, Mühlheim, Offenbach, and Offenbach in around 13h 14m.