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Philadelphia to Charleston buses

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Trip Overview

The average bus between Philadelphia and Charleston takes 21h 51m and the fastest bus takes 21h 48m. The bus runs, on average, 6 times per week from Philadelphia to Charleston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 51m
Duration
726 mi
Distance
$159
Average price
6 times a week
Frequency

Philadelphia to Charleston bus times

Buses run 6 times a week between Philadelphia and Charleston. The service departs Philadelphia at 5:50 PM in the evening, which arrives into Charleston at 15:41:43. All services require a transfer at Raleigh Bus Station and take an average of 21h 51m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USACARTACARTA21h 51m • 3 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Greyhound USAGreyhound USACARTACARTA21h 51m • 3 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAGreyhound USACARTACARTA21h 51m • 3 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USACARTACARTA21h 51m • 3 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USACARTACARTA21h 51m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USACARTACARTA21h 48m • 3 changes

Frequently asked questions

Want to know about travelling from Philadelphia to Charleston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Philadelphia to Charleston.ExpandLaunch map view
  • Distance: 725.5 mi
  • Duration: 21h 51m

What companies run services between Philadelphia, PA, USA and Charleston, SC, USA?

You can take a bus from Philadelphia Bus Station to Transit Mall via Raleigh Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 19h 12m.

Operators