Rome2Rio

Philadelphia to Florence buses

Find Transport to Florence

View schedule

Trip Overview

The average bus between Philadelphia and Florence takes 12h 48m and the fastest bus takes 11h 40m. There is at least one bus per day from Philadelphia to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 48m
Duration
550 mi
Distance
$109
Average price
Once daily
Frequency

Philadelphia to Florence bus times

Buses run once daily between Philadelphia and Florence. The earliest departure is at 7:20 PM in the evening, and the last departure from Philadelphia is at 10:00 PM which arrives into Florence at 9:40 AM. All services require a transfer at Washington Union Station and take an average of 12h 48m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA14h 20m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA14h 20m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA11h 40m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA11h 40m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA14h 20m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA11h 40m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA11h 40m • 2 changes

Frequently asked questions

Want to know about travelling from Philadelphia to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Philadelphia to Florence.ExpandLaunch map view
  • Distance: 550.1 mi
  • Duration: 12h 48m

What companies run services between Philadelphia, PA, USA and Florence, SC, USA?

You can take a bus from Philadelphia Bus Station to Florence Bus Station via Washington Union Station and Fayetteville Bus Station in around 12h 50m.

Operators