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Philadelphia to Lake City buses

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Trip Overview

The average bus between Philadelphia and Lake City takes 23h 45m and the fastest bus takes 23h 30m. The bus runs, on average, 4 times per week from Philadelphia to Lake City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 45m
Duration
922 mi
Distance
$174
Average price
4 times a week
Frequency

Philadelphia to Lake City bus times

Buses run 4 times a week between Philadelphia and Lake City. The service departs Philadelphia at 5:50 PM in the evening, which arrives into Lake City at 17:20:00. All services require a transfer at Baltimore Downtown Bus Station and take an average of 23h 45m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

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    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA23h 30m • 2 changes

Departing Saturday, October 31, 2026

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    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA24h 30m • 2 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA23h 30m • 2 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA23h 30m • 2 changes

Frequently asked questions

Want to know about travelling from Philadelphia to Lake City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Philadelphia to Lake City.ExpandLaunch map view
  • Distance: 921.7 mi
  • Duration: 23h 45m

What companies run services between Philadelphia, PA, USA and Lake City, FL, USA?

You can take a bus from Philadelphia Bus Station to Lake City Bus Station via Baltimore Downtown Bus Station and Jacksonville in around 20h 10m.

Operators