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Philadelphia to Mechanicsburg buses

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Trip Overview

The average bus between Philadelphia and Mechanicsburg takes 4h 50m and the fastest bus takes 2h 58m. The bus service runs several times per day from Philadelphia to Mechanicsburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 50m
Duration
115 mi
Distance
$25
Average price
3 times a day
Frequency

Philadelphia to Mechanicsburg bus times

Buses run 3 times a day between Philadelphia and Mechanicsburg. The earliest departure is at 9:00 AM in the morning, and the last departure from Philadelphia is at 11:55 PM which arrives into Mechanicsburg at 7:41 AM. All services require a transfer at Harrisburg Bus Station and take an average of 4h 50m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Flixbus USARabbit Transit7h 46m • 1 change

Departing Saturday, November 7, 2026

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    Greyhound USARabbit Transit3h 41m • 1 change
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    Greyhound USARabbit Transit4h 36m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    Flixbus USARabbit Transit6h 3m • 1 change

Departing Monday, November 9, 2026

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    Greyhound USARabbit Transit2h 58m • 1 change
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    Greyhound USARabbit Transit3h 23m • 1 change
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    Flixbus USARabbit Transit3h 40m • 1 change
  •  → 

    Arrives next day

    Flixbus USARabbit Transit6h 3m • 1 change

Departing Tuesday, November 10, 2026

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    Greyhound USARabbit Transit2h 58m • 1 change
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    Greyhound USARabbit Transit3h 23m • 1 change
  •  → 

    Arrives next day

    Flixbus USARabbit Transit6h 3m • 1 change

Departing Wednesday, November 11, 2026

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    Greyhound USARabbit Transit2h 58m • 1 change
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    Greyhound USARabbit Transit3h 23m • 1 change
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    Arrives next day

    Greyhound USARabbit Transit12h 23m • 1 change

Departing Thursday, November 12, 2026

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    Greyhound USARabbit Transit2h 58m • 1 change
  •  → 

    Greyhound USARabbit Transit3h 23m • 1 change
  •  → 

    Flixbus USARabbit Transit3h 40m • 1 change
  •  → 

    Arrives next day

    Greyhound USARabbit Transit12h 23m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Greyhound USARabbit Transit2h 58m • 1 change
  •  → 

    Greyhound USARabbit Transit3h 23m • 1 change
  •  → 

    Flixbus USARabbit Transit3h 40m • 1 change

Frequently asked questions

Want to know about travelling from Philadelphia to Mechanicsburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Philadelphia to Mechanicsburg.ExpandLaunch map view
  • Distance: 114.7 mi
  • Duration: 4h 50m

What companies run services between Philadelphia, PA, USA and Mechanicsburg, Cumberland County, PA, USA?

Greyhound USA operates a bus from Philadelphia Bus Station to Harrisburg Bus Station every 4 hours. Tickets cost $19–29 and the journey takes 2h. Flixbus USA also services this route 3 times a day.

Operators