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Philadelphia to Middlesex buses

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Trip Overview

The average bus between Philadelphia and Middlesex takes 4h 30m and the fastest bus takes 3h 45m. The bus service runs several times per day from Philadelphia to Middlesex. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 30m
Duration
109 mi
Distance
$27
Average price
Every 3 hours
Frequency

Bus, line 66 bus, line 114 bus

best
  1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus
  2. Take the bus from Newark Penn Station to Rt-22 At New Providence Rdbus bus 66 / ...
  3. Take the bus from Rt-22 At New Providence Rd to Boundbrook Rd At John F. Kennedy Drbus bus 114 / ...
4h 7m
$19–41

Philadelphia to Middlesex bus times

Buses run every 3 hours between Philadelphia and Middlesex. The earliest departure is at 12:30 AM at night, and the last departure from Philadelphia is at 8:45 PM which arrives into Middlesex at 1:55 AM. All services require a transfer at Newark Penn Station and take an average of 4h 30m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

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    Greyhound USANJ TransitNJ Transit5h 6m • 2 changes

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    Greyhound USANJ TransitNJ Transit4h 46m • 2 changes

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    Greyhound USANJ TransitNJ Transit4h 31m • 2 changes

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    Greyhound USANJ TransitNJ Transit5h 26m • 2 changes
  • Show more

Departing Monday, November 2, 2026

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    Flixbus USANJ TransitNJ Transit3h 45m • 2 changes

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    Greyhound USANJ TransitNJ Transit4h • 2 changes

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    Greyhound USANJ TransitNJ Transit3h 55m • 2 changes

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    Greyhound USANJ TransitNJ Transit4h 44m • 2 changes
  • Show more

Departing Tuesday, November 3, 2026

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    Flixbus USANJ TransitNJ Transit3h 45m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit3h 55m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h 44m • 2 changes
  • Show more

Departing Wednesday, November 4, 2026

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    Flixbus USANJ TransitNJ Transit7h 30m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit3h 55m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h 44m • 2 changes
  • Show more

Departing Thursday, November 5, 2026

  •  → 

    Flixbus USANJ TransitNJ Transit7h 30m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit3h 55m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h 44m • 2 changes
  • Show more

Departing Friday, November 6, 2026

  •  → 

    Flixbus USANJ TransitNJ Transit3h 45m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit3h 55m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h 44m • 2 changes
  • Show more

Departing Saturday, November 7, 2026

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    Greyhound USANJ TransitNJ Transit4h 8m • 2 changes

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    Greyhound USANJ TransitNJ Transit4h 30m • 2 changes

  •  → 

    Greyhound USANJ TransitNJ Transit4h 48m • 2 changes

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    Greyhound USANJ TransitNJ Transit4h 43m • 2 changes
  • Show more

Frequently asked questions

Want to know about travelling from Philadelphia to Middlesex? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Philadelphia to Middlesex.ExpandLaunch map view
  • Distance: 108.9 mi
  • Duration: 4h 30m

What companies run services between Philadelphia, PA, USA and Middlesex, NJ, USA?

You can take a bus from Philadelphia Bus Station to Boundbrook Rd At John F. Kennedy Dr via Newark Penn Station and Rt-22 At New Providence Rd in around 4h 7m.

Operators