The average bus between Piazza Di Spagna and Florence takes 3h 56m and the fastest bus takes 3h 35m. There is a bus service every few hours from Piazza Di Spagna to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Piazza Di Spagna and Florence. The earliest departure is at 6:29 AM in the morning, and the last departure from Piazza Di Spagna is at 10:29 PM which arrives into Florence at 2:10 AM. All services require a transfer at S. Paolo Del Brasile and take an average of 3h 56m. The schedules shown below are for the next available departures.

3h 40m • 1 change

3h 48m • 1 change

3h 37m • 1 change

4h 18m • 1 change

3h 45m • 1 change

3h 40m • 1 change

3h 42m • 1 change

4h 4m • 1 change

3h 45m • 1 change

3h 40m • 1 change

3h 42m • 1 change

4h 4m • 1 change
Want to know about travelling from Piazza Di Spagna to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Piazza Di Spagna to Florence. However, there are services departing from Piazza Di Spagna station and arriving at Florence station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 3h 56m.
Piazza Di Spagna to Florence bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Piazza Di Spagna to Florence bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Florence Villa Constanza Bus Station.
The distance between Piazza Di Spagna and Florence is 231.4 km. The road distance is 282 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €24–45 and the journey takes 3h 15m. Three other operators also service this route.