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Piazza del Duomo to Rome buses

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Trip Overview

The average bus between Piazza del Duomo and Rome takes 12h 7m and the fastest bus takes 9h 1m. There is at least one bus per day from Piazza del Duomo to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 7m
Duration
595 km
Distance
€62
Average price
Once daily
Frequency

Piazza del Duomo to Rome bus times

Buses run once daily between Piazza del Duomo and Rome. The earliest departure is at 5:19 AM in the morning, and the last departure from Piazza del Duomo is at 6:19 AM which arrives into Rome at 3:20 PM. All services require a transfer at duomo m1 m3 and take an average of 12h 7m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    ATMFlixBus9h 31m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    ATMFlixBus10h 1m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    ATMFlixBus9h 1m • 1 change

Departing Monday, November 9, 2026

  •  → 

    ATMFlixBus9h 31m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    ATMFlixBus10h 41m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    ATMFlixBus10h 41m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    ATMFlixBus10h 41m • 1 change

Frequently asked questions

Want to know about travelling from Piazza del Duomo to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Piazza del Duomo to Rome.ExpandLaunch map view
  • Distance: 595.4 km
  • Duration: 12h 7m

What companies run services between Piazza del Duomo, Lombardy, Italy and Rome, Italy?

FlixBus operates a bus from Milano, San Donato M3 to Roma, Autostazione Tiburtina every 2 hours. Tickets cost €50–80 and the journey takes 7h 30m.

Operators