The average bus between Piazza del Popolo and Milan takes 8h 32m and the fastest bus takes 7h 55m. The bus service runs several times per day from Piazza del Popolo to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Piazza del Popolo and Milan. The earliest departure is at 5:56 AM in the morning, and the last departure from Piazza del Popolo is at 11:19 PM which arrives into Milan at 8:30 AM. All services require a transfer at P.Le Flaminio and take an average of 8h 32m. The schedules shown below are for the next available departures.

8h 38m • 1 change
8h 22m • 1 change
8h 2m • 1 changeArrives next day

7h 55m • 1 change
8h 34m • 1 change
8h 31m • 1 change
8h 10m • 1 changeArrives next day

8h 2m • 1 change
8h 34m • 1 change
8h 31m • 1 change
8h 10m • 1 changeArrives next day

8h 2m • 1 changeWant to know about travelling from Piazza del Popolo to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Piazza del Popolo to Milan. However, there are services departing from Roma, Autostazione Tiburtina station and arriving at Milano, San Donato M3 station via Milano, San Donato M3 station. The journey, including transfers, takes approximately 8h 32m.
Piazza del Popolo to Milan bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Piazza del Popolo to Milan bus services, operated by FlixBus, arrive at Milano, San Donato M3 station.
The distance between Piazza del Popolo and Milan is 475.3 km. The road distance is 572 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Milano, San Donato M3 every 3 hours. Tickets cost €50–80 and the journey takes 7h 30m.