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Pilsen to Brno buses

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Trip Overview

The average bus between Pilsen and Brno takes 4h 17m and the fastest bus takes 4h. There is at least one bus per day from Pilsen to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 17m
Duration
299 km
Distance
Kč 450
Average price
Once daily
Frequency

Pilsen to Brno bus times

Buses run once daily between Pilsen and Brno. The earliest departure is at 1:50 AM at night, and the last departure from Pilsen is at 6:45 AM which arrives into Brno at 11:20 AM. All services run direct with no transfers required, and take on average 4h 17m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

  •  → 

    bus bus 4h 35m • Direct

Departing Friday, November 6, 2026

  •  → 

    bus bus 4h • Direct
  •  → 

    bus bus 4h 35m • Direct

Departing Saturday, November 7, 2026

  •  → 

    bus bus 4h • Direct
  •  → 

    bus bus 4h 35m • Direct

Departing Sunday, November 8, 2026

  •  → 

    bus bus 4h • Direct
  •  → 

    bus bus 4h 35m • Direct

Departing Monday, November 9, 2026

  •  → 

    bus bus 4h • Direct
  •  → 

    bus bus 4h 35m • Direct

Frequently asked questions

Want to know about travelling from Pilsen to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pilsen to Brno.ExpandLaunch map view
  • Distance: 299 km
  • Duration: 4h 17m

What companies run services between Pilsen, Czechia and Brno, Czechia?

FlixBus operates a bus from Plzeň to Brno once daily. Tickets cost Kč 650–1,000 and the journey takes 4h. Five other operators also service this route.

Operators