The average bus between Pisa Centrale and Roma Termini takes 5h 37m and the fastest bus takes 4h 56m. The bus service runs several times per day from Pisa Centrale to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Pisa Centrale and Roma Termini. The earliest departure is at 12:25 AM at night, and the last departure from Pisa Centrale is at 10:00 PM which arrives into Roma Termini at 2:56 AM. All services require a transfer at Pisa and take an average of 5h 37m. The schedules shown below are for the next available departures.

6h 5m • 1 change

5h 27m • 1 change

5h 45m • 1 change
Arrives next day

4h 56m • 1 change

6h 5m • 1 change

5h 27m • 1 change

5h 45m • 1 change

5h 45m • 1 change

6h 11m • 1 change

5h 16m • 1 change

5h 39m • 1 change

5h 46m • 1 change

6h 11m • 1 change

5h 16m • 1 change

5h 39m • 1 change

5h 46m • 1 change

6h 6m • 1 change

5h 27m • 1 change

5h 45m • 1 change

5h 46m • 1 change
Want to know about travelling from Pisa Centrale to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pisa Centrale to Roma Termini. However, there are services departing from Pisa Centrale station and arriving at Roma Termini station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 37m.
Pisa Centrale to Roma Termini bus services, operated by FlixBus, depart from Pisa station.
Pisa Centrale to Roma Termini bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Pisa Centrale and Roma Termini is 264.2 km. The road distance is 363 km.
FlixBus operates a bus from Pisa to Roma, Autostazione Tiburtina 3 times a day. Tickets cost €30–50 and the journey takes 5h 30m.