Rome2Rio

Pisa Centrale to Rome buses

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Trip Overview

The bus between Pisa Centrale and Rome takes 4h 45m. The bus runs, on average, 6 times per week from Pisa Centrale to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 45m
Duration
338 km
Distance
€35
Average price
6 times a week
Frequency

Pisa Centrale to Rome bus times

Buses run 6 times a week between Pisa Centrale and Rome. The service departs Pisa Centrale at 6:05 AM in the morning, which arrives into Rome at 10:50:00. All services run direct with no transfers required, and take on average 4h 45m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    bus bus 4h 45m • Direct

Departing Thursday, November 12, 2026

  •  → 

    bus bus 4h 45m • Direct

Departing Friday, November 13, 2026

  •  → 

    bus bus 4h 45m • Direct

Departing Saturday, November 14, 2026

  •  → 

    bus bus 4h 45m • Direct

Departing Sunday, November 15, 2026

  •  → 

    bus bus 4h 45m • Direct

Departing Monday, November 16, 2026

  •  → 

    bus bus 4h 45m • Direct

Frequently asked questions

Want to know about travelling from Pisa Centrale to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pisa Centrale to Rome.ExpandLaunch map view
  • Distance: 337.8 km
  • Duration: 4h 45m

What companies run services between Pisa Centrale, Italy and Rome, Italy?

FlixBus operates a bus from Pisa to Roma, Autostazione Tiburtina 3 times a day. Tickets cost €30–45 and the journey takes 4h 45m.

Operators