The average bus between Pisa and Guidonia takes 8h and the fastest bus takes 5h 53m. The bus service runs several times per day from Pisa to Guidonia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Pisa and Guidonia. The earliest departure is at 12:25 AM at night, and the last departure from Pisa is at 10:00 PM which arrives into Guidonia at 6:43 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 8h. The schedules shown below are for the next available departures.


8h 43m • 2 changes
Arrives next day


12h 48m • 2 changes
Arrives next day


8h 43m • 2 changes


6h 33m • 2 changes


5h 53m • 2 changes


7h 3m • 2 changes
Arrives next day


12h 48m • 2 changes


6h 33m • 2 changes


5h 53m • 2 changes
Arrives next day


12h 48m • 2 changes
Arrives next day


8h 43m • 2 changes
Want to know about travelling from Pisa to Guidonia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pisa to Guidonia. However, there are services departing from Pisa station and arriving at Guidonia station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 8h.
Pisa to Guidonia bus services, operated by FlixBus, depart from Pisa station.
Pisa to Guidonia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Book your Pisa to Guidonia bus tickets online with FlixBus, ATAC S.p.A. Azienda per la mobilità and Cotral S.p.A..
The distance between Pisa and Guidonia is 268.4 km. The road distance is 382 km.
FlixBus operates a bus from Pisa to Roma, Autostazione Tiburtina 3 times a day. Tickets cost €30–50 and the journey takes 5h 30m.