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Pisa to Siracusa buses

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Trip Overview

The average bus between Pisa and Siracusa takes 23h 8m and the fastest bus takes 21h 10m. The bus service runs several times per day from Pisa to Siracusa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 8m
Duration
1,230 km
Distance
€127
Average price
3 times a day
Frequency

Pisa to Siracusa bus times

Buses run 3 times a day between Pisa and Siracusa. The earliest departure is at 7:15 AM in the morning, and the last departure from Pisa is at 10:00 PM which arrives into Siracusa at 11:20 PM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 23h 8m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

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    Arrives next day

    FlixBusFlixBusInterbus21h 10m • 2 changes
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    Arrives next day

    FlixBusFlixBusInterbus25h 20m • 2 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusFlixBus26h • 2 changes
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    Arrives next day

    FlixBusFlixBusInterbus21h 10m • 2 changes
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    Arrives next day

    FlixBusFlixBusInterbus25h 20m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusFlixBus21h 15m • 2 changes
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    Arrives next day

    FlixBusFlixBusInterbus21h 10m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus25h 20m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusFlixBus21h 15m • 2 changes
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    Arrives next day

    FlixBusFlixBusInterbus21h 10m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus25h 20m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusFlixBus21h 15m • 2 changes
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    Arrives next day

    FlixBusFlixBusInterbus21h 40m • 2 changes
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    Arrives next day

    FlixBusFlixBusInterbus25h 20m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusFlixBus21h 15m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 10m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus25h 20m • 2 changes

Frequently asked questions

Want to know about travelling from Pisa to Siracusa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pisa to Siracusa.ExpandLaunch map view
  • Distance: 1,229.6 km
  • Duration: 23h 8m

What companies run services between Pisa, Italy and Siracusa, Italy?

You can take a bus from Pisa to Siracusa - Corso Umberto via Florence Villa Constanza Bus Station, Catania, and Catania Via Archimede in around 18h 6m.

Operators