Rome2Rio

Pisa to Syracuse buses

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Trip Overview

The average bus between Pisa and Syracuse takes 23h 11m and the fastest bus takes 21h 4m. The bus service runs several times per day from Pisa to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 11m
Duration
1,228 km
Distance
€124
Average price
3 times a day
Frequency

Pisa to Syracuse bus times

Buses run 3 times a day between Pisa and Syracuse. The earliest departure is at 12:00 PM in the afternoon, and the last departure from Pisa is at 10:00 PM which arrives into Syracuse at 11:14 PM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 23h 11m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 4m • 2 changes
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    Arrives next day

    FlixBusFlixBusInterbus25h 14m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 14m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 4m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus25h 14m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 14m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 4m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus25h 14m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 14m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 34m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus25h 14m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 14m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 4m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus25h 14m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 14m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus21h 4m • 2 changes
  •  → 

    Arrives next day

    FlixBusFlixBusInterbus25h 14m • 2 changes

Frequently asked questions

Want to know about travelling from Pisa to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pisa to Syracuse.ExpandLaunch map view
  • Distance: 1,227.8 km
  • Duration: 23h 11m

What companies run services between Pisa, Italy and Syracuse, Italy?

You can take a bus from Pisa to Siracusa - Von Platen via Florence Villa Constanza Bus Station, Catania, and Catania Via Archimede in around 18h 6m.

Operators