Bus Pittsburgh to Clayton from $66 | Tickets & Timetables

Pittsburgh to Clayton buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Pittsburgh and Clayton takes 9h 35m and the fastest bus takes 8h 31m. The bus service runs several times per day from Pittsburgh to Clayton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 35m
Duration: 333 mi
Distance: $66
Average price: 5 times a day
Frequency

Bus

best

Take the bus from Pittsburgh Intermodal Station to Philadelphia Bus Stationbus Greyhound US0421 / ...
Take the bus from Market St 125'W Of 10Th St to Rt-47 At Academy Stbus 313 / ...

8h 57m

$50–101

Pittsburgh to Clayton bus times

Buses run 5 times a day between Pittsburgh and Clayton. The earliest departure is at 1:40 AM at night, and the last departure from Pittsburgh is at 7:05 PM which arrives into Clayton at 7:15 AM. All services require a transfer at Philadelphia Bus Station and take an average of 9h 35m. The schedules shown below are for the next available departures.

Departing Tuesday, August 18, 2026

1:40 AM → 10:29 AM
8h 49m • 1 change
6:15 AM → 2:51 PM
8h 36m • 1 change
9:10 AM → 8:31 PM
11h 21m • 1 change
1:00 PM → 9:43 PM
8h 43m • 1 change
Show more

Departing Wednesday, August 19, 2026

1:40 AM → 10:29 AM
8h 49m • 1 change
6:15 AM → 2:51 PM
8h 36m • 1 change
9:10 AM → 8:31 PM
11h 21m • 1 change
1:00 PM → 9:43 PM
8h 43m • 1 change
Show more

Departing Thursday, August 20, 2026

1:40 AM → 10:29 AM
8h 49m • 1 change
6:15 AM → 2:51 PM
8h 36m • 1 change
9:10 AM → 8:31 PM
11h 21m • 1 change
1:00 PM → 9:43 PM
8h 43m • 1 change
Show more

Departing Friday, August 21, 2026

1:40 AM → 10:29 AM
8h 49m • 1 change
6:15 AM → 2:51 PM
8h 36m • 1 change
9:10 AM → 8:31 PM
11h 21m • 1 change
1:00 PM → 9:43 PM
8h 43m • 1 change
Show more

Departing Saturday, August 22, 2026

1:40 AM → 10:59 AM
9h 19m • 1 change
6:15 AM → 2:49 PM
8h 34m • 1 change
9:10 AM → 8:02 PM
10h 52m • 1 change
1:00 PM → 9:32 PM
8h 32m • 1 change
Show more

Departing Sunday, August 23, 2026

1:40 AM → 10:57 AM
9h 17m • 1 change
6:15 AM → 2:46 PM
8h 31m • 1 change
9:10 AM → 7:56 PM
10h 46m • 1 change
1:00 PM → 9:31 PM
8h 31m • 1 change

Frequently asked questions

Want to know about travelling from Pittsburgh to Clayton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.