The average bus between Pittsburgh and DePaul University takes 13h 45m and the fastest bus takes 10h 40m. The bus service runs several times per day from Pittsburgh to DePaul University. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Pittsburgh and DePaul University. The earliest departure is at 12:55 AM at night, and the last departure from Pittsburgh is at 7:45 PM which arrives into DePaul University at 7:08 AM. All services require a transfer at Chicago Bus Station and take an average of 13h 45m. The schedules shown below are for the next available departures.

9h 40m • 1 change

12h 27m • 1 change
Arrives next day

22h 33m • 1 change

9h 40m • 1 change

12h 27m • 1 change
Arrives next day

11h 23m • 1 change
Want to know about travelling from Pittsburgh to DePaul University? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pittsburgh to DePaul University. However, there are services departing from Pittsburgh station and arriving at DePaul University station via Chicago Bus Station station. The journey, including transfers, takes approximately 13h 45m.
Pittsburgh to DePaul University bus services, operated by Flixbus USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to DePaul University bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
The distance between Pittsburgh and DePaul University is 661.4 km. The road distance is 777 km.
Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $75–150 and the journey takes 10h 5m. Flixbus USA also services this route once daily.