Rome2Rio

Pittsburgh to Florence buses

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Trip Overview

The average bus between Pittsburgh and Florence takes 16h 31m and the fastest bus takes 14h 45m. There is at least one bus per day from Pittsburgh to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 31m
Duration
653 mi
Distance
$136
Average price
Once daily
Frequency

Pittsburgh to Florence bus times

Buses run once daily between Pittsburgh and Florence. The service departs Pittsburgh at 6:55 PM in the evening, which arrives into Florence at 09:40:00. All services require a transfer at Washington Union Station and take an average of 16h 31m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA14h 45m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA14h 45m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA14h 45m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA14h 45m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA14h 45m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA14h 45m • 2 changes

Frequently asked questions

Want to know about travelling from Pittsburgh to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pittsburgh to Florence.ExpandLaunch map view
  • Distance: 653.2 mi
  • Duration: 16h 31m

What companies run services between Pittsburgh, PA, USA and Florence, SC, USA?

You can take a bus from Pittsburgh Intermodal Station to Florence Bus Station via Washington Union Station and Raleigh Bus Station in around 14h 40m.

Operators