The average bus between Pittsburgh and Great Lakes takes 12h 21m and the fastest bus takes 10h 16m. The bus service runs several times per day from Pittsburgh to Great Lakes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Pittsburgh and Great Lakes. The earliest departure is at 12:55 AM at night, and the last departure from Pittsburgh is at 7:45 PM which arrives into Great Lakes at 6:23 AM. All services require a transfer at Chicago Bus Station and take an average of 12h 21m. The schedules shown below are for the next available departures.

9h 18m • 1 change

11h 59m • 1 change

11h 39m • 1 change
Arrives next day

10h 38m • 1 change

9h 16m • 1 change

11h 58m • 1 change

11h 40m • 1 change
Arrives next day

10h 38m • 1 change

9h 16m • 1 change

11h 58m • 1 change

11h 40m • 1 change
Arrives next day

10h 38m • 1 change
Want to know about travelling from Pittsburgh to Great Lakes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pittsburgh to Great Lakes. However, there are services departing from Pittsburgh station and arriving at Great Lakes station via Chicago Bus Station station. The journey, including transfers, takes approximately 12h 21m.
Pittsburgh to Great Lakes bus services, operated by Flixbus USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Great Lakes bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
The distance between Pittsburgh and Great Lakes is 685.7 km. The road distance is 771 km.
Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $70–140 and the journey takes 10h 5m. Flixbus USA also services this route once daily.