Rome2Rio

Pittsburgh to Manchester buses

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Trip Overview

The bus between Pittsburgh and Manchester takes 25h 25m. There is at least one bus per day from Pittsburgh to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 25m
Duration
657 mi
Distance
$134
Average price
Once daily
Frequency

Pittsburgh to Manchester bus times

Buses run once daily between Pittsburgh and Manchester. The service departs Pittsburgh at 7:00 AM in the morning, which arrives into Manchester at 07:25:00. All services require a transfer at Cincinnati and take an average of 25h 25m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Flixbus USAGo MetroTANKGreyhound USA25h 25m • 3 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Flixbus USAGo MetroTANKGreyhound USA25h 25m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Flixbus USAGo MetroTANKGreyhound USA25h 25m • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Flixbus USAGo MetroTANKGreyhound USA25h 25m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Flixbus USAGo MetroTANKGreyhound USA25h 25m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Flixbus USAGo MetroTANKGreyhound USA25h 25m • 3 changes

Frequently asked questions

Want to know about travelling from Pittsburgh to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pittsburgh to Manchester.ExpandLaunch map view
  • Distance: 657.1 mi
  • Duration: 25h 25m

What companies run services between Pittsburgh, PA, USA and Manchester, TN, USA?

You can take a bus from Pittsburgh Intermodal Station to Manchester via Cincinnati, Vine St & Martin Luther King Dr, Government Square Area B, 3rd at Main, Madison at RiverCenter, and Covington Bus Stop in around 15h 11m.

Operators