The average bus between Pittsburgh and Middletown takes 15h 25m and the fastest bus takes 13h 57m. The bus service runs several times per day from Pittsburgh to Middletown. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Pittsburgh and Middletown. The earliest departure is at 1:40 AM at night, and the last departure from Pittsburgh is at 8:00 PM which arrives into Middletown at 9:57 AM. All services require a transfer at Port Authority Bus Terminal and take an average of 15h 25m. The schedules shown below are for the next available departures.
Arrives next day


14h • 2 changes
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13h 57m • 2 changes


16h 20m • 2 changes
Arrives next day


14h • 2 changes
Arrives next day


13h 57m • 2 changes


16h 20m • 2 changes
Arrives next day


14h • 2 changes
Arrives next day


13h 57m • 2 changes


16h 20m • 2 changes
Arrives next day


14h • 2 changes
Arrives next day


13h 57m • 2 changes
Want to know about travelling from Pittsburgh to Middletown? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pittsburgh to Middletown. However, there are services departing from Pittsburgh station and arriving at Middletown station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 15h 25m.
Pittsburgh to Middletown bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Middletown bus services, operated by Greyhound USA, arrive at Hartford Union Station.
The distance between Pittsburgh and Middletown is 628.7 km. The road distance is 866 km.
You can take a bus from Pittsburgh Intermodal Station to Main St @ opp Ferry St via Port Authority Bus Terminal, Hartford Union Station, and Main St @ Gold St in around 12h 47m.