Rome2Rio

Pittsburgh to Port Saint Lucie buses

Find Transport to Port Saint Lucie

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average bus between Pittsburgh and Port Saint Lucie takes 42h 9m and the fastest bus takes 35h 57m. The bus runs, on average, 2 times per week from Pittsburgh to Port Saint Lucie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

42h 9m
Duration
1,325 mi
Distance
$261
Average price
Twice a week
Frequency

Pittsburgh to Port Saint Lucie bus times

Buses run twice a week between Pittsburgh and Port Saint Lucie. The earliest departure is at 6:30 AM in the morning, and the last departure from Pittsburgh is at 6:55 PM which arrives into Port Saint Lucie at 6:52 AM. All services require a transfer at Washington Union Station and take an average of 42h 9m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USAArea Regional Transit St Lucie2d • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USAArea Regional Transit St Lucie35h 57m • 3 changes

Frequently asked questions

Want to know about travelling from Pittsburgh to Port Saint Lucie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pittsburgh to Port Saint Lucie.ExpandLaunch map view
  • Distance: 1,324.8 mi
  • Duration: 42h 9m

What companies run services between Pittsburgh, PA, USA and Port Saint Lucie, FL, USA?

You can take a bus from Pittsburgh Intermodal Station to SW PSL Blvd & SE Bayshore Blvd via Washington Union Station, West Palm Beach Bus Station, WPB ITC at BAY D, and SW Gatlin Blvd & SW Brescia St in around 28h 54m.

Operators