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Pittsburgh to San Antonio buses

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Trip Overview

The bus between Pittsburgh and San Antonio takes 36h 30m. The bus runs, on average, 6 times per week from Pittsburgh to San Antonio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 30m
Duration
1,564 mi
Distance
$340
Average price
6 times a week
Frequency

Pittsburgh to San Antonio bus times

Buses run 6 times a week between Pittsburgh and San Antonio. The service departs Pittsburgh at 1:25 AM at night, which arrives into San Antonio at 12:55:00. All services require a transfer at Columbus and take an average of 36h 30m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA36h 30m • 3 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA36h 30m • 3 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA36h 30m • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA36h 30m • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USAFlixbus USA36h 30m • 3 changes

Frequently asked questions

Want to know about travelling from Pittsburgh to San Antonio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pittsburgh to San Antonio.ExpandLaunch map view
  • Distance: 1,564.5 mi
  • Duration: 36h 30m

What companies run services between Pittsburgh, PA, USA and San Antonio, TX, USA?

You can take a bus from Pittsburgh Intermodal Station to San Antonio Bus Station via Columbus, Nashville Bus Station, and Dallas Bus Station in around 35h 2m.

Operators