- Distance: 608.5 mi
- Duration: 13h 46m
The average bus between Pittsburgh and St. Louis takes 13h 46m and the fastest bus takes 13h 10m. The bus service runs several times per day from Pittsburgh to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Pittsburgh and St. Louis. The earliest departure is at 1:25 AM at night, and the last departure from Pittsburgh is at 7:55 PM which arrives into St. Louis at 8:15 AM. All services run direct with no transfers required, and take on average 13h 46m. The schedules shown below are for the next available departures.
Want to know about travelling from Pittsburgh to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Pittsburgh Intermodal Station and arriving at St Louis Bus Station. Services depart three times a day, and operate every day. The journey takes approximately 13h 46m.
Pittsburgh to St. Louis bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Pittsburgh to St. Louis bus tickets online with Omio and FlixBus.
The distance between Pittsburgh and St. Louis is 897.3 km. The road distance is 964 km.
Greyhound USA operates a bus from Pittsburgh Intermodal Station to St Louis Bus Station 3 times a day. Tickets cost $110–170 and the journey takes 13h 10m.
