The average bus between Plymouth and Oxford takes 7h 1m and the fastest bus takes 6h 10m. The bus service runs several times per day from Plymouth to Oxford. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Plymouth and Oxford. The earliest departure is at 12:30 AM at night, and the last departure from Plymouth is at 3:45 PM which arrives into Oxford at 10:15 PM. All services require a transfer, and take on average 7h 1m. The schedules shown below are for the next available departures.

6h 38m • 1 change

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6h 34m • 1 change

6h 10m • 1 change

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6h 10m • 1 change

7h 40m • 1 change
Want to know about travelling from Plymouth to Oxford? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Plymouth to Oxford. However, there are services departing from Plymouth station and arriving at Oxford station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 7h 1m.
Plymouth to Oxford bus services, operated by National Express, depart from Plymouth Coach Station.
Plymouth to Oxford bus services, operated by National Express, arrive at Queens Lane station.
Book your Plymouth to Oxford bus tickets online with National Express and Oxford Bus Company.
The distance between Plymouth and Oxford is 253.5 km. The road distance is 407 km.
You can take a bus from Plymouth Coach Station to Queens Lane via Heathrow Central Bus Station in around 6h 27m.