The average bus between Plymouth and Reading takes 5h 28m and the fastest bus takes 4h 29m. The bus service runs several times per day from Plymouth to Reading. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Plymouth and Reading. The earliest departure is at 12:10 PM in the afternoon, and the last departure from Plymouth is at 11:59 PM which arrives into Reading at 6:16 AM. All services require a transfer, and take on average 5h 28m. The schedules shown below are for the next available departures.

4h 44m • 1 change

5h 33m • 1 change
Arrives next day

6h 17m • 1 change

4h 44m • 1 change

5h 33m • 1 change
Arrives next day

6h 17m • 1 change

4h 44m • 1 change

5h 33m • 1 change
Arrives next day

6h 17m • 1 change
Want to know about travelling from Plymouth to Reading? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Plymouth to Reading. However, there are services departing from Plymouth station and arriving at Reading station via Reading. The journey, including transfers, takes approximately 5h 28m.
Plymouth to Reading bus services, operated by National Express, depart from Plymouth Coach Station.
Plymouth to Reading bus services, operated by National Express, arrive at Reading station.
Book your Plymouth to Reading bus tickets online with National Express, Reading Buses and FlixBus.
The distance between Plymouth and Reading is 252.9 km. The road distance is 325 km.
FlixBus operates a bus from Plymouth Coach Station to Reading twice daily. Tickets cost £23–40 and the journey takes 4h 41m. National Express also services this route once daily.