The average bus between Plymouth and Slough takes 6h and the fastest bus takes 5h 12m. The bus service runs several times per day from Plymouth to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Plymouth and Slough. The earliest departure is at 12:30 AM at night, and the last departure from Plymouth is at 3:45 PM which arrives into Slough at 8:57 PM. All services require a transfer, and take on average 6h. The schedules shown below are for the next available departures.

5h 58m • 1 change
5h 48m • 1 change
5h 29m • 1 change
6h 44m • 1 change
5h 58m • 1 change
5h 48m • 1 change
5h 29m • 1 change
6h 44m • 1 change
5h 58m • 1 change
5h 48m • 1 change
5h 29m • 1 change
6h 44m • 1 change
5h 58m • 1 change
5h 48m • 1 change
5h 29m • 1 change
6h 44m • 1 change
5h 58m • 1 change
5h 48m • 1 change
5h 29m • 1 change
6h 44m • 1 change
5h 56m • 1 change
5h 44m • 1 change
5h 15m • 1 change
6h 38m • 1 changeWant to know about travelling from Plymouth to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Plymouth to Slough. However, there are services departing from Plymouth Coach Station and arriving at Heathrow Central Bus Station via Heathrow Central Bus Station. The journey, including transfers, takes approximately 6h.
Plymouth to Slough bus services, operated by National Express, depart from Plymouth Coach Station.
Plymouth to Slough bus services, operated by National Express, arrive at Heathrow Central Bus Station.
Book your Plymouth to Slough bus tickets online with Omio.
The distance between Plymouth and Slough is 278.9 km. The road distance is 312 km.
National Express operates a bus from Plymouth Coach Station to Heathrow Central Bus Station hourly. Tickets cost £30–55 and the journey takes 4h 55m.