The average bus between Plymouth and Chicago takes 27h 39m and the fastest bus takes 22h 30m. The bus service runs several times per day from Plymouth to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Plymouth and Chicago. The earliest departure is at 4:55 AM at night, and the last departure from Plymouth is at 9:55 PM which arrives into Chicago at 6:10 AM. All services require a transfer at Boston, South Station and take an average of 27h 39m. The schedules shown below are for the next available departures.
Arrives next day


21h 30m • 2 changes
Arrives +2 days


32h 15m • 2 changes
Arrives next day


21h 30m • 2 changes
Arrives +2 days


32h 15m • 2 changes
Arrives next day


21h 30m • 2 changes
Arrives +2 days


32h 15m • 2 changes
Want to know about travelling from Plymouth to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Plymouth to Chicago. However, there are services departing from Plymouth station and arriving at Chicago station via Boston South Buses. The journey, including transfers, takes approximately 27h 39m.
Plymouth to Chicago bus services, operated by Plymouth & Brockton, depart from Park & Ride Lot, Ex 13 Info. Ctr. station.
Plymouth to Chicago bus services, operated by Plymouth & Brockton, arrive at Chicago Bus Station.
The distance between Plymouth and Chicago is 1,401 km. The road distance is 1,826 km.
You can take a bus from Park & Ride Lot, Ex 13 Info. Ctr. to Chicago Bus Station via Boston, South Station, Boston, and Newark Penn Station in around 24h 22m.