The average bus between Plymouth and Indianapolis takes 26h 18m and the fastest bus takes 22h 5m. The bus service runs several times per day from Plymouth to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Plymouth and Indianapolis. The earliest departure is at 4:55 AM at night, and the last departure from Plymouth is at 9:55 PM which arrives into Indianapolis at 3:00 AM. All services require a transfer at Boston, South Station and take an average of 26h 18m. The schedules shown below are for the next available departures.
Arrives next day


24h 5m • 2 changes
Arrives +2 days


29h 5m • 2 changes
Arrives next day


24h 5m • 2 changes
Arrives +2 days


29h 5m • 2 changes
Arrives next day


22h 5m • 2 changes
Arrives next day


24h 5m • 2 changes
Want to know about travelling from Plymouth to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Plymouth to Indianapolis. However, there are services departing from Plymouth station and arriving at Indianapolis station via Boston South Buses. The journey, including transfers, takes approximately 26h 18m.
Plymouth to Indianapolis bus services, operated by Plymouth & Brockton, depart from Park & Ride Lot, Ex 13 Info. Ctr. station.
Plymouth to Indianapolis bus services, operated by Plymouth & Brockton, arrive at Indianapolis station.
The distance between Plymouth and Indianapolis is 1,323.3 km. The road distance is 1,683 km.
You can take a bus from Park & Ride Lot, Ex 13 Info. Ctr. to Indianapolis via Boston, South Station, Boston, and Newark Penn Station in around 23h 32m.