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Port Saint Lucie to Florida buses

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Trip Overview

The average bus between Port Saint Lucie and Florida takes 6h 49m and the fastest bus takes 6h 33m. The bus runs, on average, 6 times per week from Port Saint Lucie to Florida. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 49m
Duration
272 mi
Distance
$67
Average price
6 times a week
Frequency

Port Saint Lucie to Florida bus times

Buses run 6 times a week between Port Saint Lucie and Florida. The service departs Port Saint Lucie at 8:05 AM in the morning, which arrives into Florida at 14:39:19. All services require a transfer at Kissimmee -1471 East Osceola Parkway and take an average of 6h 49m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

  •  → 

    Jet Set ExpressLynx Central Florida TransportLynx Central Florida TransportFlixbus USAJacksonville Transport6h 34m • 4 changes

Departing Wednesday, November 4, 2026

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    Jet Set ExpressLynx Central Florida TransportLynx Central Florida TransportFlixbus USAJacksonville Transport8h 5m • 4 changes

Departing Thursday, November 5, 2026

  •  → 

    Jet Set ExpressLynx Central Florida TransportLynx Central Florida TransportFlixbus USAJacksonville Transport6h 34m • 4 changes

Departing Friday, November 6, 2026

  •  → 

    Jet Set ExpressLynx Central Florida TransportLynx Central Florida TransportFlixbus USAJacksonville Transport6h 34m • 4 changes

Departing Saturday, November 7, 2026

  •  → 

    Jet Set ExpressLynx Central Florida TransportLynx Central Florida TransportFlixbus USAJacksonville Transport6h 33m • 4 changes

Departing Monday, November 9, 2026

  •  → 

    Jet Set ExpressLynx Central Florida TransportLynx Central Florida TransportFlixbus USAJacksonville Transport6h 34m • 4 changes

Frequently asked questions

Want to know about travelling from Port Saint Lucie to Florida? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Port Saint Lucie to Florida.ExpandLaunch map view
  • Distance: 272.2 mi
  • Duration: 6h 49m

What companies run services between Port Saint Lucie, FL, USA and Florida, USA?

You can take a bus from Fort Pierce to Newnan St + Ashley St via Kissimmee -1471 East Osceola Parkway, Osceola Pkwy Walmart, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, Jacksonville, and JRTC Bay J in around 8h 18m.

Operators