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Port Saint Lucie to Key Biscayne buses

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Trip Overview

The bus between Port Saint Lucie and Key Biscayne takes 4h 11m. There is at least one bus per day from Port Saint Lucie to Key Biscayne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 11m
Duration
126 mi
Distance
$41
Average price
Once daily
Frequency

Port Saint Lucie to Key Biscayne bus times

Buses run once daily between Port Saint Lucie and Key Biscayne. The service departs Port Saint Lucie at 8:45 AM in the morning, which arrives into Key Biscayne at 12:56:20. All services require a transfer at Bayside Marketplace and take an average of 4h 11m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Jet Set ExpressMiami Dade TransitMiami Dade Transit4h 11m • 2 changes

Departing Friday, November 13, 2026

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    Jet Set ExpressMiami Dade TransitMiami Dade Transit4h 11m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Jet Set ExpressMiami Dade TransitMiami Dade Transit4h 12m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Jet Set ExpressMiami Dade TransitMiami Dade Transit4h 12m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Jet Set ExpressMiami Dade TransitMiami Dade Transit4h 11m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Jet Set ExpressMiami Dade TransitMiami Dade Transit4h 11m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Jet Set ExpressMiami Dade TransitMiami Dade Transit4h 11m • 2 changes

Frequently asked questions

Want to know about travelling from Port Saint Lucie to Key Biscayne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Port Saint Lucie to Key Biscayne.ExpandLaunch map view
  • Distance: 125.9 mi
  • Duration: 4h 11m

What companies run services between Port Saint Lucie, FL, USA and Key Biscayne, FL, USA?

Jet Set Express operates a bus from Fort Pierce to Bayside Marketplace once daily. Tickets cost $30–40 and the journey takes 2h 55m.

Operators