The average bus between Portimão and Santarém takes 5h 18m and the fastest bus takes 4h 35m. The bus service runs several times per day from Portimão to Santarém. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Portimão and Santarém. The earliest departure is at 8:10 AM in the morning, and the last departure from Portimão is at 10:00 PM which arrives into Santarém at 5:55 AM. All services require a transfer, and take on average 5h 18m. The schedules shown below are for the next available departures.

4h 35m • 1 change

4h 45m • 1 change

5h 15m • 1 change
Arrives next day

4h 45m • 1 change

4h 35m • 1 change

4h 45m • 1 change

5h 15m • 1 change
Arrives next day

4h 45m • 1 change

4h 35m • 1 change

4h 45m • 1 change

5h 15m • 1 change
Arrives next day

4h 45m • 1 change

4h 35m • 1 change

4h 45m • 1 change

5h 15m • 1 change
Arrives next day

4h 45m • 1 change

4h 35m • 1 change

4h 45m • 1 change

5h 15m • 1 change
Arrives next day

4h 45m • 1 change
Want to know about travelling from Portimão to Santarém? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portimão to Santarém. However, there are services departing from Portimão station and arriving at Santarém station via Lisbon. The journey, including transfers, takes approximately 5h 18m.
Portimão to Santarém bus services, operated by FlixBus, depart from Terminal Rodoviário de Portimão station.
Portimão to Santarém bus services, operated by FlixBus, arrive at Santarem station.
Book your Portimão to Santarém bus tickets online with FlixBus.
The distance between Portimão and Santarém is 233.3 km. The road distance is 347 km.
You can take a bus from Terminal Rodoviário de Portimão to Santarem via Lisbon in around 5h 15m.