The average bus between Portland and Boston takes 3h 26m and the fastest bus takes 3h. The bus service runs several times per day from Portland to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Portland and Boston. The earliest departure is at 7:39 AM in the morning, and the last departure from Portland is at 7:28 PM which arrives into Boston at 10:40 PM. All services require a transfer at Central Row @ Main St and take an average of 3h 26m. The schedules shown below are for the next available departures.


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3h 29m • 2 changesWant to know about travelling from Portland to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to Boston. However, there are services departing from Main St @ Rappallo Ave station and arriving at Boston station via Main St @ 750 Main St station. The journey, including transfers, takes approximately 3h 26m.
Portland to Boston bus services, operated by CT Transit, depart from Main St @ Rappallo Ave station.
Portland to Boston bus services, operated by Greyhound USA, arrive at Boston station.
The distance between Portland and Boston is 157.2 km. The road distance is 180 km.
You can take a bus from Main St @ Rappallo Ave to Boston via Central Row @ Main St and Hartford Union Station in around 3h 33m.