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Portland to Des Moines buses

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Trip Overview

The average bus between Portland and Des Moines takes 40h 29m and the fastest bus takes 33h 40m. The bus service runs several times per day from Portland to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

40h 29m
Duration
1,554 mi
Distance
Twice daily
Frequency

Bus

best
  1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
  2. Take the bus from Boston to New York Midtownbus bus
  3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
  4. Take the bus from Chicago to Des Moinesbus bus
32h 48m

Portland to Des Moines bus times

Buses run twice daily between Portland and Des Moines. The earliest departure is at 12:30 PM in the afternoon, and the last departure from Portland is at 8:00 PM which arrives into Des Moines at 6:10 PM. All services require a transfer at Boston, MA - South Station and take an average of 40h 29m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Portland to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Portland to Des Moines.ExpandLaunch map view
  • Distance: 1,554.3 mi
  • Duration: 40h 29m

What companies run services between Portland, ME, USA and Des Moines, IA, USA?

You can take a bus from Portland, ME to Des Moines via Boston, MA - South Station, Boston, New York Midtown, and Chicago in around 32h 48m.

Operators