The average bus between Portland and Des Moines takes 2d 1h and the fastest bus takes 47h 45m. The bus service runs several times per day from Portland to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Portland and Des Moines. The earliest departure is at 11:30 AM in the morning, and the last departure from Portland is at 8:00 PM which arrives into Des Moines at 6:45 PM. All services require a transfer at Boston, MA - South Station and take an average of 2d 1h. The schedules shown below are for the next available departures.
Want to know about travelling from Portland to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to Des Moines. However, there are services departing from Portland, ME station and arriving at Des Moines station via Boston, MA - South Station, New York Midtown station and Chicago Bus Station. The journey, including transfers, takes approximately 2 days 1h.
Portland to Des Moines bus services, operated by Concord Coach Lines, depart from Portland, ME station.
Portland to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Book your Portland to Des Moines bus tickets online with Omio.
The distance between Portland and Des Moines is 1917.5 km. The road distance is 2176 km.
You can take a bus from Portland, ME to Des Moines via Boston, MA - South Station, Boston, New York Midtown, and Chicago Bus Station in around 36h 3m.
