Portland to Guilford Buses

Portland to Guilford buses

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Trip Overview

The average bus between Portland and Guilford takes 8h 46m and the fastest bus takes 7h 9m. The bus service runs several times per day from Portland to Guilford. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 46m
Duration: 262 mi
Distance: $53
Average price: 4 times a day
Frequency

Bus

best

Take the bus from Portland, ME to Boston, MA - South Stationbus
Take the bus from Boston to Hartford Union Stationbus
Take the bus from Spruce St @ Union Station Bus Terminal to State St @ Court Stbus 950

8h 21m

$41–75

Portland to Guilford bus times

Buses run 4 times a day between Portland and Guilford. The earliest departure is at 6:15 AM in the morning, and the last departure from Portland is at 8:00 PM which arrives into Guilford at 8:37 AM. All services require a transfer at Boston, MA - South Station and take an average of 8h 46m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

8:00 PM → 8:37 AM
Arrives next day
12h 37m • 3 changes

Departing Monday, November 2, 2026

6:15 AM → 2:48 PM
8h 33m • 3 changes
8:30 AM → 3:39 PM
7h 9m • 3 changes
9:30 AM → 5:39 PM
8h 9m • 3 changes
10:30 AM → 6:43 PM
8h 13m • 3 changes
Show more

Departing Tuesday, November 3, 2026

6:15 AM → 2:48 PM
8h 33m • 3 changes
8:30 AM → 3:39 PM
7h 9m • 3 changes
10:30 AM → 6:43 PM
8h 13m • 3 changes
12:30 PM → 8:15 PM
7h 45m • 3 changes
Show more

Departing Wednesday, November 4, 2026

6:15 AM → 2:48 PM
8h 33m • 3 changes
8:30 AM → 3:39 PM
7h 9m • 3 changes
9:30 AM → 5:39 PM
8h 9m • 3 changes
10:30 AM → 6:43 PM
8h 13m • 3 changes
Show more

Departing Thursday, November 5, 2026

6:15 AM → 2:48 PM
8h 33m • 3 changes
8:30 AM → 3:39 PM
7h 9m • 3 changes
9:30 AM → 5:39 PM
8h 9m • 3 changes
10:30 AM → 6:43 PM
8h 13m • 3 changes
Show more

Departing Friday, November 6, 2026

6:15 AM → 2:48 PM
8h 33m • 3 changes
8:30 AM → 3:39 PM
7h 9m • 3 changes
9:30 AM → 5:39 PM
8h 9m • 3 changes
10:30 AM → 6:43 PM
8h 13m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Portland to Guilford? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus