The average bus between Portland and Holyoke takes 5h 44m and the fastest bus takes 4h 14m. The bus service runs several times per day from Portland to Holyoke. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Portland and Holyoke. The earliest departure is at 4:15 AM at night, and the last departure from Portland is at 8:00 PM which arrives into Holyoke at 6:41 AM. All services require a transfer at Boston, MA - South Station and take an average of 5h 44m. The schedules shown below are for the next available departures.


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4h 14m • 2 changesWant to know about travelling from Portland to Holyoke? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to Holyoke. However, there are services departing from Portland station and arriving at Holyoke station via Boston, MA - South Station station. The journey, including transfers, takes approximately 5h 44m.
Portland to Holyoke bus services, operated by Concord Coach Lines, depart from Portland, ME station.
Portland to Holyoke bus services, operated by Concord Coach Lines, arrive at Springfield Union Station.
The distance between Portland and Holyoke is 250.9 km. The road distance is 325 km.
You can take a bus from Portland, ME to HTC Bay 7 via Boston, MA - South Station, Boston, Springfield Union Station, and Union Station Bay 9 in around 4h 50m.