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Portland to Irvine buses

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Trip Overview

The average bus between Portland and Irvine takes 3d 7h and the fastest bus takes 3d 5h. The bus runs, on average, 5 times per week from Portland to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3d 7h
Duration
3,308 mi
Distance
$695
Average price
5 times a week
Frequency

Portland to Irvine bus times

Buses run 5 times a week between Portland and Irvine. The service departs Portland at 3:30 PM in the afternoon, which arrives into Irvine at 04:46:01. All services require a transfer at Boston, MA - South Station and take an average of 3d 7h. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

  •  → 

    Arrives +4 days

    Concord Coach LinesPeter Pan Bus LinesGreyhound USAGreyhound USAFlixbus USAOCTA3d 16h • 5 changes

Departing Friday, October 23, 2026

  •  → 

    Arrives +3 days

    Concord Coach LinesPeter Pan Bus LinesGreyhound USAGreyhound USAGreyhound USAOCTA3d 5h • 5 changes

Departing Saturday, October 24, 2026

  •  → 

    Arrives +3 days

    Concord Coach LinesPeter Pan Bus LinesGreyhound USAGreyhound USAGreyhound USAOCTA3d 5h • 5 changes

Departing Sunday, October 25, 2026

  •  → 

    Arrives +3 days

    Concord Coach LinesPeter Pan Bus LinesGreyhound USAGreyhound USAGreyhound USAOCTA3d 5h • 5 changes

Frequently asked questions

Want to know about travelling from Portland to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Portland to Irvine.ExpandLaunch map view
  • Distance: 3,308.5 mi
  • Duration: 3d 7h

What companies run services between Portland, ME, USA and Irvine, CA, USA?

You can take a bus from Portland, ME to Main-Harvard via Boston, MA - South Station, Boston, New York, Port Authority Bus Terminal, St Louis Bus Station, Los Angeles Union Station, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 3d 3h.

Operators