The average bus between Portland and Minneapolis–Saint Paul takes 42h and the fastest bus takes 36h 4m. The bus service runs several times per day from Portland to Minneapolis–Saint Paul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Portland and Minneapolis–Saint Paul. The earliest departure is at 12:30 PM in the afternoon, and the last departure from Portland is at 8:00 PM which arrives into Minneapolis–Saint Paul at 6:20 PM. All services require a transfer at Boston, MA - South Station and take an average of 42h. The schedules shown below are for the next available departures.
Arrives +2 days




41h 51m • 4 changes
Arrives +2 days




46h 26m • 4 changes
Arrives +2 days




36h 4m • 4 changes
Arrives +2 days




46h 26m • 4 changes
Want to know about travelling from Portland to Minneapolis–Saint Paul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to Minneapolis–Saint Paul. However, there are services departing from Portland station and arriving at Minneapolis–Saint Paul station via Boston, MA - South Station station. The journey, including transfers, takes approximately 42h.
Portland to Minneapolis–Saint Paul bus services, operated by Amtrak Thruway, depart from Portland, ME station.
Portland to Minneapolis–Saint Paul bus services, operated by Amtrak Thruway, arrive at Saint Paul Union Depot station.
The distance between Portland and Minneapolis–Saint Paul is 1,825.1 km. The road distance is 2,632 km.
You can take a bus from Portland, ME to Marshall & Otis Station via Boston, MA - South Station, Boston, New York Midtown, Chicago Bus Station, Saint Paul Union Depot, and Union Depot & Gate A1 in around 34h 28m.