The average bus between Portland and New Orleans takes 42h 23m and the fastest bus takes 39h. The bus service runs several times per day from Portland to New Orleans. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Portland and New Orleans. The earliest departure is at 3:30 PM in the afternoon, and the last departure from Portland is at 8:00 PM which arrives into New Orleans at 4:50 PM. All services require a transfer at Boston, MA - South Station and take an average of 42h 23m. The schedules shown below are for the next available departures.
Arrives +2 days



38h • 3 changes
Arrives +2 days



44h 50m • 3 changes
Arrives +2 days



38h • 3 changes
Arrives +2 days



44h 50m • 3 changes
Arrives +2 days



38h • 3 changes
Arrives +2 days



44h 50m • 3 changes
Arrives +2 days



38h • 3 changes
Arrives +2 days



44h 50m • 3 changes
Want to know about travelling from Portland to New Orleans? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to New Orleans. However, there are services departing from Portland station and arriving at New Orleans station via Boston, MA - South Station station. The journey, including transfers, takes approximately 42h 23m.
Portland to New Orleans bus services, operated by Amtrak Thruway, depart from Portland, ME station.
Portland to New Orleans bus services, operated by Amtrak Thruway, arrive at New Orleans Bus Station.
Book your Portland to New Orleans bus tickets online with Amtrak Thruway, Flixbus USA and 2 other operators.
The distance between Portland and New Orleans is 2,320.1 km. The road distance is 2,795 km.
You can take a bus from Portland, ME to New Orleans Bus Station via Boston, MA - South Station, Boston, New York Midtown, and Atlanta Bus Station in around 36h 28m.