Rome2Rio

Portland to Santa Cruz buses

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Trip Overview

The average bus between Portland and Santa Cruz takes 20h 44m and the fastest bus takes 20h 31m. There is at least one bus per day from Portland to Santa Cruz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 44m
Duration
738 mi
Distance
$157
Average price
Once daily
Frequency

Portland to Santa Cruz bus times

Buses run once daily between Portland and Santa Cruz. The service departs Portland at 7:05 PM in the evening, which arrives into Santa Cruz at 15:36:00. All services require a transfer at Sacramento Bus Station and take an average of 20h 44m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USASanta Cruz Metro20h 31m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USASanta Cruz Metro21h 17m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USASanta Cruz Metro21h 17m • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USASanta Cruz Metro20h 31m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USASanta Cruz Metro20h 31m • 3 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAGreyhound USASanta Cruz Metro20h 31m • 3 changes

Frequently asked questions

Want to know about travelling from Portland to Santa Cruz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Portland to Santa Cruz.ExpandLaunch map view
  • Distance: 737.7 mi
  • Duration: 20h 44m

What companies run services between Portland, OR, USA and Santa Cruz, CA, USA?

You can take a bus from Portland Curbside Bus Stop to Soquel Ave & Front via Sacramento Bus Station, Oakland, San Jose Diridon Station, and Diridon Station in around 18h 53m.

Operators