The average bus between Portland and South Lake Union takes 4h 6m and the fastest bus takes 3h 48m. The bus service runs several times per day from Portland to South Lake Union. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Portland and South Lake Union. The earliest departure is at 6:20 AM in the morning, and the last departure from Portland is at 7:10 PM which arrives into South Lake Union at 11:02 PM. All services require a transfer at Seattle Bus Station and take an average of 4h 6m. The schedules shown below are for the next available departures.

4h 14m • 1 change
4h 4m • 1 change
3h 48m • 1 change
4h 18m • 1 change
4h 34m • 1 change
4h 4m • 1 change
3h 49m • 1 change
4h 48m • 1 changeWant to know about travelling from Portland to South Lake Union? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portland to South Lake Union. However, there are services departing from Portland Curbside Bus Stop station and arriving at Seattle Bus Station via Seattle Bus Station. The journey, including transfers, takes approximately 4h 6m.
Portland to South Lake Union bus services, operated by Greyhound USA, depart from Portland Curbside Bus Stop station.
Portland to South Lake Union bus services, operated by Greyhound USA, arrive at Seattle Bus Station.
The distance between Portland and South Lake Union is 235 km. The road distance is 281 km.
Greyhound USA operates a bus from Portland Curbside Bus Stop to Seattle Bus Station twice daily. Tickets cost $30–50 and the journey takes 3h 10m. Flixbus USA also services this route twice daily.