The average bus between Portsmouth and Cape Cod takes 7h 42m and the fastest bus takes 3h 58m. The bus service runs several times per day from Portsmouth to Cape Cod. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Portsmouth and Cape Cod. The earliest departure is at 12:55 AM at night, and the last departure from Portsmouth is at 6:50 PM which arrives into Cape Cod at 6:48 AM. All services require a transfer at Boston and take an average of 7h 42m. The schedules shown below are for the next available departures.


7h 53m • 2 changes


3h 58m • 2 changes
Arrives next day


11h 58m • 2 changes


7h 53m • 2 changes


3h 58m • 2 changes
Arrives next day


11h 58m • 2 changes


7h 53m • 2 changes


3h 58m • 2 changes
Arrives next day


11h 58m • 2 changes
Want to know about travelling from Portsmouth to Cape Cod? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Portsmouth to Cape Cod. However, there are services departing from Portsmouth station and arriving at Cape Cod station via Boston. The journey, including transfers, takes approximately 7h 42m.
Portsmouth to Cape Cod bus services, operated by Greyhound-us, depart from Portsmouth Bus Stop station.
Portsmouth to Cape Cod bus services, operated by Greyhound-us, arrive at Hyannis Transportation Center station.
The distance between Portsmouth and Cape Cod is 162 km. The road distance is 220 km.
You can take a bus from Portsmouth Bus Stop to Town Hall Lawton Bus Shelter via Boston, South Station Transp. Ctr, and Hyannis Transportation Center in around 4h 40m.