The average bus between Poway and La Mesa takes 2h 30m and the fastest bus takes 2h 6m. There is a bus service every few hours from Poway to La Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Poway and La Mesa. The earliest departure is at 5:00 AM in the morning, and the last departure from Poway is at 6:59 PM which arrives into La Mesa at 9:43 PM. All services require a transfer at Sabre Springs & Penasquitos Transit Station and take an average of 2h 30m. The schedules shown below are for the next available departures.



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2h 9m • 3 changesWant to know about travelling from Poway to La Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Poway to La Mesa. However, there are services departing from Poway station and arriving at La Mesa station via Fashion Valley Transit Center. The journey, including transfers, takes approximately 2h 30m.
Poway to La Mesa bus services, operated by San Diego Metro Transit, depart from Miramar College Transit Station.
Poway to La Mesa bus services, operated by San Diego Metro Transit, arrive at University Av & Allison Av station.
The distance between Poway and La Mesa is 21.7 km. The road distance is 55 km.
You can take a bus from Hilleary Pl & Hilleary Park Dr to University Av & Allison Av via Sabre Springs & Penasquitos Transit Station, Miramar College Transit Station, and Fashion Valley Transit Center in around 2h 43m.