Prague 1 to Brno bus times
Buses run hourly between Prague 1 and Brno. The earliest departure is at 12:10 AM at night, and the last departure from Prague 1 is at 10:50 PM which arrives into Brno at 1:55 AM. All services require a transfer at Florenc and take an average of 3h 9m. The schedules shown below are for the next available departures.
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Arrives next day
3h 8m • 1 change
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Arrives next day
3h 5m • 1 change
Departing Monday, August 10, 2026
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6h • 1 change
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3h 4m • 1 change
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2h 59m • 1 change
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2h 56m • 1 change
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Departing Tuesday, August 11, 2026
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6h • 1 change
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3h 4m • 1 change
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2h 59m • 1 change
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2h 56m • 1 change
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