Prague 1 to Brno Buses

Prague 1 to Brno buses

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Trip Overview

The average bus between Prague 1 and Brno takes 3h 13m and the fastest bus takes 2h 48m. There is a bus service every few hours from Prague 1 to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 13m
Duration: 219 km
Distance: Kč 584
Average price: Hourly
Frequency

Bus

best

Take the bus from Praha, ÚAN Florenc to Brnobus 850 / ...

3h 36m

Kč 359–739

Prague 1 to Brno bus times

Buses run hourly between Prague 1 and Brno. The earliest departure is at 7:27 AM in the morning, and the last departure from Prague 1 is at 8:27 PM which arrives into Brno at 11:55 PM. All services require a transfer at Florenc and take an average of 3h 13m. The schedules shown below are for the next available departures.

Departing Wednesday, October 28, 2026

8:27 PM → 11:55 PM
3h 28m • 1 change

Departing Thursday, October 29, 2026

7:27 AM → 10:30 AM
3h 3m • 1 change
7:42 AM → 11:00 AM
3h 18m • 1 change
8:12 AM → 11:20 AM
3h 8m • 1 change
8:42 AM → 11:55 AM
3h 13m • 1 change
Show more

Departing Friday, October 30, 2026

7:27 AM → 10:30 AM
3h 3m • 1 change
7:42 AM → 11:00 AM
3h 18m • 1 change
8:12 AM → 11:20 AM
3h 8m • 1 change
8:42 AM → 11:55 AM
3h 13m • 1 change
Show more

Departing Saturday, October 31, 2026

7:27 AM → 10:30 AM
3h 3m • 1 change
7:57 AM → 11:20 AM
3h 23m • 1 change
8:27 AM → 11:55 AM
3h 28m • 1 change
8:57 AM → 12:10 PM
3h 13m • 1 change
Show more

Departing Sunday, November 1, 2026

7:27 AM → 10:30 AM
3h 3m • 1 change
7:57 AM → 11:20 AM
3h 23m • 1 change
8:27 AM → 11:55 AM
3h 28m • 1 change
8:57 AM → 12:10 PM
3h 13m • 1 change
Show more

Departing Monday, November 2, 2026

7:27 AM → 10:30 AM
3h 3m • 1 change
7:42 AM → 11:00 AM
3h 18m • 1 change
8:12 AM → 11:20 AM
3h 8m • 1 change
8:42 AM → 11:55 AM
3h 13m • 1 change
Show more

Departing Tuesday, November 3, 2026

7:27 AM → 10:30 AM
3h 3m • 1 change
7:42 AM → 11:00 AM
3h 18m • 1 change
8:12 AM → 11:20 AM
3h 8m • 1 change
8:42 AM → 11:55 AM
3h 13m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Prague 1 to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus