The average bus between Prague Airport (PRG) and Nové Mesto takes 6h 2m and the fastest bus takes 5h 39m. The bus service runs several times per day from Prague Airport (PRG) to Nové Mesto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Prague Airport (PRG) and Nové Mesto. The earliest departure is at 12:37 AM at night, and the last departure from Prague Airport (PRG) is at 5:05 PM which arrives into Nové Mesto at 11:53 PM. All services require a transfer at Hlavní nádraží and take an average of 6h 2m. The schedules shown below are for the next available departures.


5h 42m • 2 changes


6h 7m • 2 changes


5h 39m • 2 changes


5h 54m • 2 changes


5h 42m • 2 changes


6h 7m • 2 changes


5h 39m • 2 changes


5h 54m • 2 changes


5h 42m • 2 changes


6h 7m • 2 changes


5h 39m • 2 changes


5h 39m • 2 changes


5h 42m • 2 changes


6h 7m • 2 changes


5h 39m • 2 changes


5h 54m • 2 changes


5h 42m • 2 changes


6h 7m • 2 changes


5h 39m • 2 changes


5h 54m • 2 changes


5h 42m • 2 changes


6h 12m • 2 changes


5h 39m • 2 changes


5h 54m • 2 changes
Want to know about travelling from Prague Airport (PRG) to Nové Mesto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prague Airport (PRG) to Nové Mesto. However, there are services departing from Prague Airport (PRG) station and arriving at Nové Mesto station via Bratislava, Autobusová stanica Mlynské Nivy. The journey, including transfers, takes approximately 6h 2m.
Prague Airport (PRG) to Nové Mesto bus services, operated by Pražská integrovaná doprava, depart from Praha, Hlavní Nádraží station.
Prague Airport (PRG) to Nové Mesto bus services, operated by Pražská integrovaná doprava, arrive at Bratislava, Autobusová stanica Mlynské Nivy station.
The distance between Prague Airport (PRG) and Nové Mesto is 300.2 km. The road distance is 358 km.
FlixBus operates a bus from Praha, Hlavní Nádraží to Bratislava, Autobusová stanica Mlynské Nivy every 4 hours. Tickets cost €28–50 and the journey takes 4h 30m.