The average bus between Prague Main Train Station and Brno takes 2h 31m and the fastest bus takes 2h 25m. The bus service runs several times per day from Prague Main Train Station to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Prague Main Train Station and Brno. The earliest departure is at 1:45 AM at night, and the last departure from Prague Main Train Station is at 11:25 PM which arrives into Brno at 1:55 AM. All services run direct with no transfers required, and take on average 2h 31m. The schedules shown below are for the next available departures.
Want to know about travelling from Prague Main Train Station to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Prague Main Train Station station and arriving at Brno station. Services depart every 3 hours, and operate Once daily. The journey takes approximately 2h 31m.
Prague Main Train Station to Brno bus services, operated by FlixBus, depart from Praha, Hlavní Nádraží station.
Prague Main Train Station to Brno bus services, operated by FlixBus, arrive at Brno station.
Book your Prague Main Train Station to Brno bus tickets online with FlixBus.
The distance between Prague Main Train Station and Brno is 185 km. The road distance is 206 km.
FlixBus operates a bus from Praha, Hlavní Nádraží to Brno every 3 hours. Tickets cost Kč 430–750 and the journey takes 2h 35m. České dráhy (ČD) also services this route twice a week.