The average bus between Prague and Brussel-Zuid / Bruxelles-Midi takes 14h 35m and the fastest bus takes 12h. The bus service runs several times per day from Prague to Brussel-Zuid / Bruxelles-Midi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Prague and Brussel-Zuid / Bruxelles-Midi. The earliest departure is at 4:15 PM in the afternoon, and the last departure from Prague is at 11:05 PM which arrives into Brussel-Zuid / Bruxelles-Midi at 1:55 PM. All services run direct with no transfers required, and take on average 14h 35m. The schedules shown below are for the next available departures.
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Want to know about travelling from Prague to Brussel-Zuid / Bruxelles-Midi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Prague station and arriving at Brussel-Zuid / Bruxelles-Midi station. Services depart twice daily, and operate Twice daily. The journey takes approximately 14h 35m.
Prague to Brussel-Zuid / Bruxelles-Midi bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Brussel-Zuid / Bruxelles-Midi bus services, operated by FlixBus, arrive at Brussels South station.
Book your Prague to Brussel-Zuid / Bruxelles-Midi bus tickets online with FlixBus and RegioJet.
The distance between Prague and Brussel-Zuid / Bruxelles-Midi is 718.1 km. The road distance is 945 km.
FlixBus operates a bus from Praha, ÚAN Florenc to Brussels South twice daily. Tickets cost €80–140 and the journey takes 15h 5m. RegioJet also services this route 4 times a week.