The average bus between Prague and Karlstein takes 5h 26m and the fastest bus takes 4h 38m. The bus service runs several times per day from Prague to Karlstein. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Prague and Karlstein. The earliest departure is at 5:20 AM in the morning, and the last departure from Prague is at 9:40 PM which arrives into Karlstein at 6:48 AM. All services require a transfer at Regensburg central train station and take an average of 5h 26m. The schedules shown below are for the next available departures.

6h 38m • 1 change

6h 40m • 1 change

5h 25m • 1 change
Arrives next day

9h 8m • 1 change

6h 38m • 1 change

6h 40m • 1 change

5h 25m • 1 change
Arrives next day

9h 8m • 1 change

6h 38m • 1 change

6h 40m • 1 change

5h 25m • 1 change
Arrives next day

9h 8m • 1 change
Want to know about travelling from Prague to Karlstein? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Prague to Karlstein. However, there are services departing from Prague station and arriving at Karlstein station via Regensburg central train station station. The journey, including transfers, takes approximately 5h 26m.
Prague to Karlstein bus services, operated by BlaBlaCar Bus, depart from Prague station.
Prague to Karlstein bus services, operated by BlaBlaCar Bus, arrive at Regensburg central train station.
The distance between Prague and Karlstein is 192.4 km. The road distance is 257 km.
FlixBus operates a bus from Prague to Regensburg central train station every 4 hours. Tickets cost €20–35 and the journey takes 3h 25m. BlaBlaCar Bus also services this route twice daily.